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Several natural supplements have been shown to boost the brain. As we have emphasized, a funding initiative does not by itself make a particular set of scientific problems immediately tractable, nor does it ensure effective handoffs from academic or government scientists to industry or the development of safe and effective preventive interventions or treatments. An excellent example of such an unexpected benefit is the diverse science underpinning intelligent learning systems, which has led to an enormous number of applications, such as speech-recognition technology and powerful data-analysis tools that are used throughout academe, many industries, and government. Federal government creates Royal Commission on Health Services to study need for health insurance and health services; appoints Emmet M. Hall as Chair. This can be a benefit for people who need to gain weight or increase appetite, such as people with cancer receiving chemotherapy. However, in addition to supporting relevant research directly, funding initiatives can attract established researchers to a field, influence the popularity of a field among trainees, and gain the attention of academic and industrial developers of technology. The key factors that now motivate a proposal for an initiative on brain disorders are the rapidly advancing tools and knowledge to facilitate understanding of disease mechanisms, a strong and growing scientific workforce in neuroscience, and a substantial mismatch between research investment and unmet medical need, global disease burden, and rising costs to societies (Bloom et al., 2011; Murray et al., 2013). The need for research investment is highlighted by the growing global prevalence and costs of neurodegenerative disorders (Hebert et al., 2013; Hurd et al., 2013) and a large disinvestment by industry in brain disorders since 2010 (Choi et al., 2014) with the possible exception of Alzheimer disease clinical trials.
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